Hypercholesterolemia is characterized by high plasma LDL cholesterol and often caused by genetic mutations in LDL receptor (LDLR), APOB, or proprotein convertase subtilisin/kexin type 9 (PCSK9).However, a substantial proportion of hypercholesterolemic subjects do not have any mutations in these canonical genes, leaving the underlying pathobiology t
Release of dye-containing textile wastewater into the environment causes severe pollution with serious consequences on aquatic life.Bioremediation of dyes using thermophilic microorganisms has tv bracket recently attracted attention over conventional treatment techniques.Thermophiles have the natural ability to survive under extreme environmental c
INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a rare, progressive neurodegenerative disease.There is heterogeneity of clinical phenotypes while a clinical characterization of ALS in Cyprus is still lacking.The aim of this 30-year retrospective study of ALS in Cyprus is to determine the demographic characteristics Lord of the Rings of patients
Mutations in the INSR gene result in rare Collections inherited syndromes causing insulin resistance, such as leprechaunism (Donohue syndrome), Rabson-Mendenhall syndrome and insulin resistance type A.Leprechaunism is an autosomal recessive disorder associated with extreme insulin resistance that leads to hyperinsulinemia, impaired glucose homeosta